ENZYMATIC SYNTHESIS OF DESOXYRIBOSE NUCLEOSIDE WITH DESOXYRIBOSE PHOSPHATE ESTER
نویسندگان
چکیده
منابع مشابه
Enzymatic synthesis of thiouracil riboside and thiouracil desoxyriboside.
In a survey of various substrates for pyrimidine nucleoside synthesis, it was noted that inorganic orthophosphate was released when 2-thiouracil and desoxyribose-l-phosphate were incubated together with thymidine phosphorylase (1). This finding, taken as a fairly certain indication of nucleoside synthesis, has now been fully substantiated by isolation and characterization of crystalline thioura...
متن کاملChromosin, a Desoxyribose Nucleoprotein Complex of the Cell Nucleus
A desoxyribose nucleoprotein complex, which we have referred to as a chromosin, has been prepared from a great variety of cells, mainly animal but also plant and bacterial. A chromosin is derived from the cell nucleus. In the course of preparation precautions have been taken to prevent contamination by cytoplasmic constituents. To assure the nuclear origin of all components of chromosin, nuclei...
متن کاملInterrelationships between ribose and desoxyribose components of nucleic acids.
LactobaciUus bifidus (Lactobacilus acidophilus ATCC 4963) was previously reported (Skeggs et al., 1949) to require for growth, in an otherwise complete medium, either vitamin B12, thymine desoxyriboside, or intact desoxyribonucleic acid (DNA). The growth of L. bidus in the presence of DNA was found (Skeggs et al., 1950)1 to be inhibited competitively by yeast ribonucleic acid (RNA). Subsequent ...
متن کاملEnzymatic synthesis of nucleoside diphosphates and triphosphates.
It has been recognized from recent studies that nucleoside triphosphates, other than ATP,’ function in biologic systems as phosphorylating agents (1) and in coenzyme synthesis (2) in a manner analogous to that of ATP. The discovery of the natural occurrence of a variety of purine and pyrimidine nucleoside diand triphosphates (3-5) and the likelihood that new biologic functions for these nucleot...
متن کاملEnzymatic Synthesis of Acetyl Phosphate*
In order to prove this suggestion, a study of the chemistry of acetyl phosphate was undertaken and eventually a method of determination and a simple synthesis were worked out (3). With these available, on oxidation of pyruvate the appearance of a labile organic phosphate was observed (4) which closely resembled acetyl phosphate. The present, communication reports upon t.he isolation of this int...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56987-8